RAF Typhoon fighter aircraft have operated alongside France's air force in a joint strike on an hidden munitions depot in Syrian territory operated by the IS group, per a report from the British defence ministry.
The site, identified by intelligence, was believed to be containing munitions and bombs, the announcement noted, and was positioned in mountains just above the historic site of Palmyra in Syria's central region.
"Our aircraft used laser-guided Paveway IV weapons to strike a series of entry passages leading to the depot... initial indications indicate the target was engaged successfully," officials stated.
There was no indication of any civilian impact in the strike conducted Saturday night and all the aircraft returned to base without incident, the defence officials confirmed.
The British jets were backed up by a Voyager tanker plane.
The Islamic State group - referred to as ISIS - established extremist governance over parts of both Syria and Iraq until 2019.
"This action demonstrates the UK's leading role, and resolve to operate in unison with allied nations, to stamp out any resurgence of the terrorist group and their violent and radical beliefs in the Middle East," Britain's Defence Chief the minister said.
UK warplanes have carried out overwatch operations over Syrian airspace to "deter any efforts to regroup" of the group following its military defeat at the climactic battle in Baghuz in the year 2019, the MoD reported.
"I must thank every member of the UK armed forces who took part in this operation for their professionalism and their bravery," the Defence Secretary added. "They were part of numerous British troops on duty over the holidays. This action, to take out terrorist threats who threaten our way of life, highlights how UK forces are always on standby, continuously, ensuring Britain's security within its borders and strong abroad."
During December, the US military carried out what it called a "large-scale strike" targeting IS targets in the country, after an ambush killed two US troops and a civilian interpreter in Palmyra.
The UN reports IS still boasts an estimated 5,000 to 7,000 combatants in Syria and Iraq.